tuberculosis: treatment-related problems and future facets
نویسندگان
چکیده
tuberculosis is an infectious disease caused by mycobacterium tuberculosis and is the primary cause of mortality in the world. m. tuberculosis strains are important intracellular pathogens causing infection in oxygen-rich macrophages in the lungs. the emergence of aids, declined socioeconomic standards and a lessened emphasis on tb control programs have contributed to the disease resurgence. resistance of m. tuberculosis strains to anti-tb agents is an increasing problem worldwide. however, powerful new anti-tb drugs with new mechanisms of action have not been developed in the last 40 years, in spite of acute toxicity of repeated dosing of the available anti-tb drugs.
منابع مشابه
Tuberculosis: Past, Present and Future
Background Tuberculosis (TB) is the second-most common cause of death from infectious disease (after those due to HIV/AIDS). Roughly one-third of the world's population has been infected with M. tuberculosis, with new infections occurring in about 1% of the population each year. People with active TB can infect 10-15 other people through close contact over the course of a year. Materials and ...
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عنوان ژورنال:
archives of clinical infectious diseasesجلد ۸، شماره ۲، صفحات ۰-۰
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